Description

Methyl 3-Amino-2-Bromo-5-Fluorobenzoate is a high-purity, multi-functional halogenated benzoate ester, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates amino, bromo, and fluoro substituents on an aromatic ring, enabling precise structural modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: The amino and halogen groups make it a valuable scaffold for creating novel ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated aromatic intermediates.

Basic Information

Product Name	Methyl 3-Amino-2-Bromo-5-Fluorobenzoate
CAS No.	1342063-52-8
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	3-Amino-2-bromo-5-fluorobenzoic acid methyl ester; Methyl 3-amino-2-bromo-5-fluorobenzoate; 2-Bromo-5-fluoro-3-aminobenzoic acid methyl ester; Benzoic acid, 3-amino-2-bromo-5-fluoro-, methyl ester; Methyl 2-bromo-5-fluoro-3-aminobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-2-Bromo-5-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in regulated research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.