Description

2-Methanesulfonyl-3-Methyl-3H-Imidazo[4,5-B]Pyridine is a high-purity heterocyclic building block featuring a fused imidazopyridine core functionalized with a methanesulfonyl group. This compound matters as a critical advanced intermediate in modern pharmaceutical research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small-molecule drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure.
• Chemical Biology Probe Development: Serves as a core scaffold for designing molecular probes to study biological pathways and protein functions.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	2-Methanesulfonyl-3-Methyl-3H-Imidazo[4,5-B]Pyridine
CAS No.	1341039-98-2
Molecular Formula	C9H9N3O2S
Molecular Weight	223.25 g/mol
Synonyms	3-Methyl-2-(methylsulfonyl)-3H-imidazo[4,5-b]pyridine; 2-Methanesulfonyl-3-methylimidazo[4,5-b]pyridine; 3-Methyl-2-(methanesulfonyl)imidazo[4,5-b]pyridine; 2-Methylsulfonyl-3-methyl-3H-imidazo[4,5-b]pyridine; Imidazo[4,5-b]pyridine, 3-methyl-2-(methylsulfonyl)-; 1341039-98-2
EINECS	Contact for details

Quality Control

Our 2-Methanesulfonyl-3-Methyl-3H-Imidazo[4,5-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.