Description

8-(Boc-Amino)-2-Azaspiro[4.5]Decane is a high-purity, protected amine building block of significant importance in modern organic synthesis. This compound is valued for its rigid spirocyclic scaffold and the presence of a Boc-protected amino group, which provides orthogonal reactivity and stability under a wide range of reaction conditions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of novel, complex molecular architectures in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Peptidomimetic Chemistry: Used to introduce constrained, spirocyclic motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Agrochemical Research: Utilized as a synthetic intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Potential monomer or cross-linking agent for creating specialty polymers with unique thermal and mechanical properties.

Basic Information

Product Name	8-(Boc-Amino)-2-Azaspiro[4.5]Decane
CAS No.	1341038-05-8
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	8-[(tert-Butoxycarbonyl)amino]-2-azaspiro[4.5]decane; tert-Butyl (2-azaspiro[4.5]decan-8-yl)carbamate; N-Boc-8-amino-2-azaspiro[4.5]decane; 8-(tert-Butoxycarbonylamino)-2-azaspiro[4.5]decane; 2-Azaspiro[4.5]decan-8-amine, N-Boc-protected; Boc-8-Amino-2-azaspiro[4.5]decane; CAS 1341038-05-8
EINECS	Contact for details

Quality Control

Our 8-(Boc-Amino)-2-Azaspiro[4.5]Decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0% (by titration)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.