Description

tert-Butyl 7-Amino-2-Azaspiro[4.4]Nonane-2-Carboxylate CAS NO 1341037-08-8 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with enhanced biological activity and selectivity. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the creation of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) for investigational drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in drug discovery programs.
• Protease Inhibitor Development: Serves as a core structural element in the design of novel protease inhibitors.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for target validation studies.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in complex, stereoselective synthetic routes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Item	Details
Product Name	tert-Butyl 7-Amino-2-Azaspiro[4.4]Nonane-2-Carboxylate
CAS No.	1341037-08-8
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	7-Amino-2-azaspiro[4.4]nonane-2-carboxylic acid tert-butyl ester; 2-Azaspiro[4.4]nonane-2-carboxylic acid, 7-amino-, 1,1-dimethylethyl ester; tert-Butyl 7-amino-2-azaspiro[4.4]nonane-2-carboxylate; 2-(tert-Butoxycarbonyl)-2-azaspiro[4.4]nonan-7-amine; Boc-2-azaspiro[4.4]nonan-7-amine; (7-Amino-2-azaspiro[4.4]non-2-yl)-tert-butyl carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Amino-2-Azaspiro[4.4]Nonane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports development from research to commercial scale, with the capability to meet cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.