Description

tert-Butyl 8-Hydroxy-2-Azaspiro[4.5]Decane-2-Carboxylate is a high-value, protected amino alcohol derivative featuring a spirocyclic structure. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Chiral Auxiliary/Synthon: Utilized in asymmetric synthesis to induce chirality and create enantiomerically pure compounds.
• Agrochemical Research: Intermediate for developing new generation pesticides and herbicides with complex molecular architectures.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in metal-catalyzed reactions.
• Peptidomimetics and Bioisosteres: The spirocyclic and protected amino alcohol motifs are valuable in designing peptide mimics and bioisosteric replacements.
• Academic and R&D Laboratories: Used in methodological studies and for exploring new synthetic routes to complex heterocycles.

Basic Information

Product Name	tert-Butyl 8-Hydroxy-2-Azaspiro[4.5]Decane-2-Carboxylate
CAS No.	1341036-10-9
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	8-Hydroxy-2-azaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; tert-Butyl 8-hydroxy-2-azaspiro[4.5]decane-2-carboxylate; 2-Azaspiro[4.5]decane-2-carboxylic acid, 8-hydroxy-, 1,1-dimethylethyl ester; 2-tert-Butoxycarbonyl-8-hydroxy-2-azaspiro[4.5]decane; Boc-8-hydroxy-2-azaspiro[4.5]decane; 8-Hydroxy-2-Boc-2-azaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-Hydroxy-2-Azaspiro[4.5]Decane-2-Carboxylate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.