Description

1-(9H-Fluoren-9-Ylmethyl) 4-Methyl Piperidine-1,4-Dicarboxylate is a specialized organic building block featuring a fluorenylmethyl (Fmoc-like) protecting group and a piperidine dicarboxylate core. This compound matters as a high-value intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), peptidomimetics, and other advanced organic compounds where selective protection and functionalization are critical.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, especially those targeting neurological or metabolic pathways.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs where the piperidine moiety can mimic proteinogenic amino acids or introduce conformational constraints.
• Organic Synthesis Scaffold: Provides a versatile platform for further chemical modifications due to its reactive ester groups and protected amine functionality.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies and the development of new synthetic routes.
• Custom Synthesis Projects: Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule production.

Basic Information

Product Name	1-(9H-Fluoren-9-Ylmethyl) 4-Methyl Piperidine-1,4-Dicarboxylate
CAS No.	1340322-21-5
Molecular Formula	C24H25NO4
Molecular Weight	391.46 g/mol
Synonyms	1-[(9H-Fluoren-9-yl)methyl] 4-methyl piperidine-1,4-dicarboxylate; 4-Methyl 1-[(9H-fluoren-9-yl)methyl] piperidine-1,4-dicarboxylate; 1-Fmoc-4-methyl piperidine-1,4-dicarboxylate; 1-(9-Fluorenylmethyl) 4-methyl piperidine-1,4-dicarboxylate; Piperidine-1,4-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 4-methyl ester; Fmoc-piperidine-4-carboxylic acid methyl ester (common abbreviation); 1,4-Piperidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl)-, 4-methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics are available upon request. We adhere to a cGMP-compliant quality management system for products intended for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Keep the container tightly sealed in a desiccator for long-term storage to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.