Description

[6-(2-Hydroxyethoxy)Pyridin-3-Yl]Boronic Acid Pinacol Ester is a high-purity, functionalized pyridine boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the creation of organic electronic materials, including ligands for OLEDs and conductive polymers.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura coupling to form biaryl and heterobiaryl bonds, a cornerstone of medicinal chemistry.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex target molecules.

Basic Information

Product Name	[6-(2-Hydroxyethoxy)Pyridin-3-Yl]Boronic Acid Pinacol Ester
CAS No.	1339926-59-8
Molecular Formula	C13H20BNO4
Molecular Weight	265.11 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-hydroxyethoxy)pyridine; 2-(2-Hydroxyethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; (6-(2-Hydroxyethoxy)pyridin-3-yl)boronic acid pinacol ester; Pinacol [6-(2-hydroxyethoxy)pyridin-3-yl]boronate; Boronic acid, B-[6-(2-hydroxyethoxy)-3-pyridinyl]-, 1,1-dimethylethyl ester; 6-(2-Hydroxyethoxy)-3-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our [6-(2-Hydroxyethoxy)Pyridin-3-Yl]Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.