Description

Methyl 4-Fluoro-3-Methyl-5-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced organic synthesis. Its molecular structure, featuring strategically placed fluorine, methyl, and nitro substituents, makes it a valuable precursor for developing complex molecules in life sciences research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a critical intermediate for synthesizing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, ester hydrolysis, and nitro group reduction sequences to create diverse chemical libraries.
• Chemical Research & Development: Essential for academic and industrial research exploring new fluorination methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 4-Fluoro-3-Methyl-5-Nitrobenzoate
CAS No.	1339408-08-0
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Benzoic acid, 4-fluoro-3-methyl-5-nitro-, methyl ester; Methyl 4-fluoro-3-methyl-5-nitrobenzoate; 4-Fluoro-3-methyl-5-nitrobenzoic acid methyl ester; 3-Methyl-4-fluoro-5-nitrobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Fluoro-3-Methyl-5-Nitrobenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.