Description

4-(3-tert-Butyl-1,2,4-Oxadiazol-5-Yl)-2-Chloropyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its unique oxadiazole-pyridine hybrid scaffold.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Potential precursor for ligands in catalysis or for creating functional organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-(3-tert-Butyl-1,2,4-Oxadiazol-5-Yl)-2-Chloropyridine
CAS No.	1338675-20-9
Molecular Formula	C11H12ClN3O
Molecular Weight	237.69 g/mol
Synonyms	2-Chloro-4-(3-tert-butyl-1,2,4-oxadiazol-5-yl)pyridine; 2-Chloro-4-(3-(tert-butyl)-1,2,4-oxadiazol-5-yl)pyridine; 4-(3-tert-Butyl-1,2,4-oxadiazol-5-yl)-2-chloropyridine; 5-(6-Chloropyridin-3-yl)-3-(tert-butyl)-1,2,4-oxadiazole; CAS 1338675-20-9
EINECS	Contact for details

Quality Control

Our 4-(3-tert-Butyl-1,2,4-Oxadiazol-5-Yl)-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.