Description

(5-Iodo-3-Nitro-Pyridin-2-Yl)-Methyl-Amine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated and nitrated pyridine structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential monomer or precursor for synthesizing specialty polymers and functional materials.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Nucleophilic Substitution: The nitro and amine groups provide handles for further functionalization and ring modification.

Basic Information

Product Name	(5-Iodo-3-Nitro-Pyridin-2-Yl)-Methyl-Amine
CAS No.	1338652-31-5
Molecular Formula	C6H6IN3O2
Molecular Weight	279.04 g/mol
Synonyms	2-Amino-5-iodo-3-nitropyridine; 5-Iodo-3-nitro-2-pyridinamine; N-Methyl-5-iodo-3-nitropyridin-2-amine; (5-Iodo-3-nitropyridin-2-yl)methylamine; 2-Pyridinamine, 5-iodo-3-nitro-; 5-Iodo-3-nitro-2-aminopyridine; 2-Amino-5-iodo-3-nitropyridine; 5-Iodo-3-nitropyridin-2-amine
EINECS	Contact for details

Quality Control

Our (5-Iodo-3-Nitro-Pyridin-2-Yl)-Methyl-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (NMR, IR), and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.