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(5-(4-Chlorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)(2,6-Difluoro-3-(Propylsulfonylmethyl)Phenyl)Methanone CAS NO 1338247-73-6


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CAS No.:1338247-73-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(5-(4-Chlorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)(2,6-Difluoro-3-(Propylsulfonylmethyl)Phenyl)Methanone is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapies. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on oncology, neurology, and other therapeutic areas requiring complex heterocyclic scaffolds.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex fused-ring system.
  • API Development: Serves as a core scaffold for developing active pharmaceutical ingredients targeting specific disease pathways.
  • Biochemical Tool Compound: Utilized in vitro and in vivo to study biological mechanisms and validate novel drug targets.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name (5-(4-Chlorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)(2,6-Difluoro-3-(Propylsulfonylmethyl)Phenyl)Methanone
CAS No. 1338247-73-6
Molecular Formula C24H17ClF2N2O3S
Molecular Weight 486.92 g/mol
Synonyms 1338247-73-6; Methanone, (5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)(2,6-difluoro-3-[(propylsulfonyl)methyl]phenyl)-; (5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)(2,6-difluoro-3-((propylsulfonyl)methyl)phenyl)methanone; (5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)[2,6-difluoro-3-(propylsulfonylmethyl)phenyl]methanone
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Quality Control

Our (5-(4-Chlorophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)(2,6-Difluoro-3-(Propylsulfonylmethyl)Phenyl)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong alkalis and fluorides; ensure it is stored separately from such materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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