Description

Methyl 4-(1-((tert-Butoxycarbonyl)Amino)Cyclopropyl)Benzoate is a high-purity, advanced pharmaceutical intermediate featuring a cyclopropylamine core protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel therapeutic agents, particularly in the areas of protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Protease Inhibitor Development: Serves as a crucial scaffold in the research and production of protease inhibitors, including those for viral targets.
• Medicinal Chemistry & Drug Discovery: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in early-stage drug discovery programs.
• Peptidomimetic Synthesis: Employed in the construction of peptidomimetics, where the cyclopropyl and benzoate groups mimic natural peptide structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials.
• Academic Research: Used in university and institutional labs for investigating new synthetic methodologies and biological mechanisms.

Basic Information

Product Name	Methyl 4-(1-((tert-Butoxycarbonyl)Amino)Cyclopropyl)Benzoate
CAS No.	1338243-88-1
Molecular Formula	C16H21NO4
Molecular Weight	291.34 g/mol
Synonyms	4-(1-((tert-Butoxycarbonyl)amino)cyclopropyl)benzoic acid methyl ester; Methyl 4-[1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopropyl]benzoate; Boc-Cyclopropylaminobenzoate Methyl Ester; Methyl 4-(1-(Boc-amino)cyclopropyl)benzoate; 4-(1-(Boc-amino)cyclopropyl)benzoic acid methyl ester; Boc-ACPB Methyl Ester; 1338243-88-1
EINECS	Contact for details

Quality Control

Our Methyl 4-(1-((tert-Butoxycarbonyl)Amino)Cyclopropyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.