Description

(S)-n-(Pyridin-2-Ylmethyl)Piperidin-3-Amine Trihydrochloride is a high-purity, chiral amine derivative supplied as a trihydrochloride salt. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up of new chemical entities (NCEs) requiring a specific (S)-configured amine moiety.
• Biochemical Tool Compound: May be employed in the development of biochemical probes and assay reagents for target validation studies.
• Catalyst Ligand Synthesis: Potential use as a precursor for synthesizing chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	(S)-n-(Pyridin-2-Ylmethyl)Piperidin-3-Amine Trihydrochloride
CAS No.	1338222-43-7
Molecular Formula	C12H22Cl3N3
Molecular Weight	314.68 g/mol
Synonyms	(S)-2-((Piperidin-3-ylamino)methyl)pyridine trihydrochloride; (S)-N-(Pyridin-2-ylmethyl)piperidin-3-amine trihydrochloride; (S)-3-Amino-1-(2-pyridylmethyl)piperidine trihydrochloride; (S)-1-((Pyridin-2-yl)methyl)piperidin-3-amine trihydrochloride; (S)-N-(2-Pyridylmethyl)-3-piperidinamine trihydrochloride; (S)-3-[(Pyridin-2-ylmethyl)amino]piperidine trihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-n-(Pyridin-2-Ylmethyl)Piperidin-3-Amine Trihydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.