Description

n-((5-Bromopyridin-3-Yl)Methyl)Ethanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyridine core structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted drug candidates with enhanced biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for central nervous system (CNS) and oncology applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, particularly those targeting protein kinases and other enzymes.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile bromopyridine scaffold.
• CNS Drug Development: Employed in the research and development of potential therapeutics for neurological disorders.
• Oncology Research: Acts as a building block for compounds being investigated for anti-cancer properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	n-((5-Bromopyridin-3-Yl)Methyl)Ethanamine Dihydrochloride
CAS No.	1337882-65-1
Molecular Formula	C8H12BrCl2N2
Molecular Weight	296.00 g/mol
Synonyms	N-[(5-Bromopyridin-3-yl)methyl]ethanamine dihydrochloride; 2-[(5-Bromo-3-pyridinyl)methyl]aminoethane dihydrochloride; Ethanamine, N-[(5-bromo-3-pyridinyl)methyl]-, dihydrochloride; 5-Bromo-3-[(ethylamino)methyl]pyridine dihydrochloride; 3-[(Ethylaminomethyl)]-5-bromopyridine dihydrochloride; (5-Bromo-3-pyridylmethyl)ethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our n-((5-Bromopyridin-3-Yl)Methyl)Ethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.