Description

2-Propanone, 1-Amino-1-(1H-Pyrrolo[3,2-C]Pyridin-4-Yl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small molecule drugs, particularly in oncology and neurology.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Kinase Inhibitor Development: Used in the construction of potential kinase inhibitors due to its pyrrolopyridine moiety.
• Bioconjugation & Probe Synthesis: The amino and ketone functional groups allow for conjugation chemistry to create biochemical probes.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory drug discovery projects.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-Propanone, 1-Amino-1-(1H-Pyrrolo[3,2-C]Pyridin-4-Yl)-
CAS No.	1337852-20-6
Molecular Formula	C10H11N3O
Molecular Weight	189.22 g/mol
Synonyms	1-Amino-1-(1H-pyrrolo[3,2-c]pyridin-4-yl)propan-2-one; 4-(1-Amino-2-oxopropyl)-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 1-amino-1-(1H-pyrrolo[3,2-c]pyridin-4-yl)-2-propanone; 1-Amino-1-(1H-pyrrolo[3,2-c]pyridin-4-yl)acetone; CAS 1337852-20-6
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-Amino-1-(1H-Pyrrolo[3,2-C]Pyridin-4-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.