Description

5-Fluoro-2-Methoxy-3-(Pyrrolidin-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial importance for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of central nervous system (CNS) and oncology therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex active pharmaceutical ingredients.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic & Institutional Research: Used in university and institutional labs for pharmacological and biochemical research.

Basic Information

Product Name	5-Fluoro-2-Methoxy-3-(Pyrrolidin-2-Yl)Pyridine
CAS No.	1337444-35-5
Molecular Formula	C10H13FN2O
Molecular Weight	196.22 g/mol
Synonyms	3-(Pyrrolidin-2-yl)-5-fluoro-2-methoxypyridine; 5-Fluoro-2-methoxy-3-(2-pyrrolidinyl)pyridine; 2-Methoxy-5-fluoro-3-(pyrrolidin-2-yl)pyridine; 5-Fluoro-2-methoxy-3-pyrrolidin-2-ylpyridine; 1337444-35-5
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxy-3-(Pyrrolidin-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and support regulatory filings. Certificates of Analysis (COA) detailing all test results are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.