Description

2-Azido-2-(6-Chlorophenyl-2,3,4,5-D4)-Cyclohexanone is a deuterated organic compound featuring an azido functional group and a chlorinated aromatic ring. This compound is of significant value as a stable isotope-labeled intermediate in the synthesis of novel pharmaceuticals and agrochemicals, enabling critical pharmacokinetic and metabolic studies. It is primarily needed by research institutions and development laboratories in the pharmaceutical, biotechnology, and agrochemical sectors for advanced analytical and synthetic applications.

Application

• Pharmaceutical Research: As a deuterium-labeled building block for the synthesis of novel drug candidates, enabling metabolic stability studies and the development of deuterated drugs.
• Metabolite Identification: Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification and metabolite tracking in biological matrices.
• Agrochemical Development: Serves as a key intermediate in the research and synthesis of new, labeled pesticide or herbicide molecules.
• Mechanistic Studies: Employed in chemical reaction mechanism elucidation, leveraging the kinetic isotope effect (KIE) of the deuterium atoms.
• Organic Synthesis: Utilized in click chemistry and other azide-alkyne cycloaddition reactions to construct complex molecular architectures.
• Analytical Reference Standard: Provides a high-purity certified reference material for method development and validation in analytical laboratories.

Basic Information

Product Name	2-Azido-2-(6-Chlorophenyl-2,3,4,5-D4)-Cyclohexanone
CAS No.	1336986-09-4
Molecular Formula	C12H9D4ClN3O
Molecular Weight	247.72 g/mol
Synonyms	2-Azido-2-(6-chlorophenyl-d4)cyclohexanone; 2-Azido-2-(6-chloro-d4-phenyl)cyclohexanone; 6-Chlorophenyl-2,3,4,5-d4-2-azidocyclohexanone; Cyclohexanone, 2-azido-2-(6-chlorophenyl-2,3,4,5-d4)-; Deuterated 2-Azido-2-(6-chlorophenyl)cyclohexanone
EINECS	Contact for details

Quality Control

Our 2-Azido-2-(6-Chlorophenyl-2,3,4,5-D4)-Cyclohexanone is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is analyzed using advanced techniques including NMR, HPLC, and LC-MS to confirm identity, chemical purity, and deuterium incorporation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Keep away from heat, sparks, and open flames. Due to the azide functional group, handle and store away from strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Deuterium Incorporation (NMR/LC-MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.