Description

(S)-3-(4-Bromophenyl)Piperidine CAS NO 1335523-82-4 is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical and agrochemical research. Its value lies in its enantiomeric purity and the versatile reactivity of the bromophenyl and piperidine moieties, enabling the synthesis of complex, biologically active molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of central nervous system (CNS) active drugs, including potential analgesics, antipsychotics, and antidepressants.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the (S)-enantiomer may offer specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, crucial for producing enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Academic and Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic organic chemistry.
• Process Chemistry & Scale-up: Used in the optimization and pilot-scale production of active pharmaceutical ingredients (APIs) requiring this specific chiral scaffold.

Basic Information

Product Name	(S)-3-(4-Bromophenyl)Piperidine
CAS No.	1335523-82-4
Molecular Formula	C11H14BrN
Molecular Weight	240.14 g/mol
Synonyms	(S)-3-(4-Bromophenyl)piperidine; (3S)-3-(4-Bromophenyl)piperidine; (S)-3-(p-Bromophenyl)piperidine; (S)-3-(4-Bromo-phenyl)-piperidine; 4-Bromo-α-pipecoline; (S)-4-Bromo-α-pipecoline; (S)-3-(4-Bromophenyl)piperidine hydrochloride (salt form); (S)-3-(4-Bromophenyl)piperidine HBr (salt form)
EINECS	Contact for details

Quality Control

Every batch of (S)-3-(4-Bromophenyl)Piperidine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet the highest standards. Our quality commitment includes providing a detailed Certificate of Analysis (COA) with each shipment, which typically includes data for chiral purity (HPLC), chemical purity (HPLC/GC), residual solvents, and other critical parameters. We support development from milligram to kilogram scale with consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.