Description

Ethyl 2-(2-Cyanophenyl)-2,2-Difluoroacetate is a high-purity, specialized fluorinated building block essential for advanced organic synthesis. This compound matters for its unique difluoroacetate ester moiety adjacent to a cyano-substituted aromatic ring, enabling precise molecular modifications in complex chemical architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and cyclizations to introduce the difluoroacetate functional group.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and the properties of fluorinated molecules.

Basic Information

Product Name	Ethyl 2-(2-Cyanophenyl)-2,2-Difluoroacetate
CAS No.	1335290-31-7
Molecular Formula	C11H9F2NO2
Molecular Weight	225.19 g/mol
Synonyms	2-(2-Cyanophenyl)-2,2-difluoroacetic Acid Ethyl Ester; Ethyl 2,2-Difluoro-2-(2-cyanophenyl)acetate; 2-Cyanobenzyl Difluoroacetate Ethyl Ester; α,α-Difluoro-2-cyanobenzeneacetic Acid Ethyl Ester; Ethyl α,α-Difluoro-2-cyanophenylacetate; Difluoro(2-cyanophenyl)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2-Cyanophenyl)-2,2-Difluoroacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.