Description

6-Bromo-5-Chloronicotinamide is a high-value halogenated nicotinamide derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for functionalized polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The bromo and chloro substituents make it a suitable substrate for palladium-catalyzed reactions like Suzuki and Buchwald-Hartwig couplings.

Basic Information

Product Name	6-Bromo-5-Chloronicotinamide
CAS No.	1335059-22-7
Molecular Formula	C6H4BrClN2O
Molecular Weight	235.47 g/mol
Synonyms	5-Chloro-6-bromonicotinamide; Nicotinamide, 6-bromo-5-chloro-; 6-Bromo-5-chloro-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 6-bromo-5-chloro-; 6-Bromo-5-chloropyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloronicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.