Description

5-Bromo-2-Chloro-3-Isopropoxy-Pyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile chemical handle for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical companies offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-Bromo-2-Chloro-3-Isopropoxy-Pyridine
CAS No.	1335058-63-3
Molecular Formula	C9H11BrClNO
Molecular Weight	264.55 g/mol
Synonyms	3-Isopropoxy-5-bromo-2-chloropyridine; 2-Chloro-5-bromo-3-isopropoxypyridine; 5-Bromo-2-chloro-3-(1-methylethoxy)pyridine; 5-Bromo-2-chloro-3-(propan-2-yloxy)pyridine; 1335058-63-3; Pyridine, 5-bromo-2-chloro-3-(1-methylethoxy)-; 3-(Isopropoxy)-5-bromo-2-chloropyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-3-Isopropoxy-Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.