Description

3-Pyridineacetic Acid, 2-Chloro-α,α-Difluoro-, Methyl Ester is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both chloro and difluoro substituents, enabling precise modifications in complex chemical architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorinated pyridine core contributes to enhanced biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-Pyridineacetic Acid, 2-Chloro-α,α-Difluoro-, Methyl Ester
CAS No.	1335057-40-3
Molecular Formula	C9H8ClF2NO2
Molecular Weight	235.61 g/mol
Synonyms	Methyl 2-Chloro-α,α-difluoro-3-pyridineacetate; 2-Chloro-α,α-difluoro-3-pyridineacetic Acid Methyl Ester; Methyl (2-Chloro-3-pyridyl)difluoroacetate; 2-Chloro-3-pyridyl(difluoro)acetic Acid Methyl Ester; (2-Chloro-3-pyridyl)difluoroacetic Acid Methyl Ester; 1335057-40-3; Methyl 2-chloro-α,α-difluoronicotinate
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridineacetic Acid, 2-Chloro-α,α-Difluoro-, Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.