Description

5-Bromo-2-Chloro-3-(Pyrrolidin-1-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated pyridine core substituted with a pyrrolidine moiety. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Serves as a key scaffold for developing new-generation herbicides and pesticides with improved efficacy and selectivity.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in heterocyclic chemistry.
• Ligand and Catalyst Development: The nitrogen-rich structure makes it suitable for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	5-Bromo-2-Chloro-3-(Pyrrolidin-1-Yl)Pyridine
CAS No.	1335056-00-2
Molecular Formula	C9H10BrClN2
Molecular Weight	261.55 g/mol
Synonyms	5-Bromo-2-chloro-3-(1-pyrrolidinyl)pyridine; 2-Chloro-5-bromo-3-pyrrolidin-1-ylpyridine; 3-(Pyrrolidin-1-yl)-5-bromo-2-chloropyridine; 1335056-00-2; 5-Bromo-2-chloro-3-pyrrolidin-1-yl-pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-3-(Pyrrolidin-1-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.