Description

4,5-Dichloropicolinonitrile is a high-purity, halogenated heterocyclic nitrile building block of significant importance in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the dichloropyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized heterocycles for organic electronic materials and advanced polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services (CDMO) catering to specific client R&D projects.
• Academic and Industrial R&D: Utilized in exploratory chemistry for method development and creating libraries of novel chemical entities for screening.

Basic Information

Product Name	4,5-Dichloropicolinonitrile
CAS No.	1335055-88-3
Molecular Formula	C6H2Cl2N2
Molecular Weight	172.99 g/mol
Synonyms	4,5-Dichloro-2-cyanopyridine; 4,5-Dichloropyridine-2-carbonitrile; 2-Cyano-4,5-dichloropyridine; Picolinonitrile, 4,5-dichloro-; 4,5-Dichloro-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4,5-Dichloropicolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.