Description

Ethyl 6-Bromo-4-Chloronicotinate is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its unique halogenated pyridine structure makes it a critical building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Serves as a versatile building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used in the research and preparation of specialized ligands and organometallic catalysts for cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for advanced materials, such as organic semiconductors and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	Ethyl 6-Bromo-4-Chloronicotinate
CAS No.	1335054-04-0
Molecular Formula	C8H7BrClNO2
Molecular Weight	264.50 g/mol
Synonyms	Ethyl 6-bromo-4-chloropyridine-3-carboxylate; 4-Chloro-6-bromonicotinic acid ethyl ester; 3-Pyridinecarboxylic acid, 6-bromo-4-chloro-, ethyl ester; 6-Bromo-4-chloronicotinic acid ethyl ester; Ethyl 4-chloro-6-bromonicotinate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-Bromo-4-Chloronicotinate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profile via techniques like HPLC, GC, and NMR, is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.