Description

1,6-Dichloro-2,7-Naphthyridine is a high-purity, halogenated naphthyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its versatile reactivity, where the chlorine atoms provide excellent handles for further functionalization, enabling the construction of complex heterocyclic architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the naphthyridine core for bioactivity.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex substituents onto the naphthyridine scaffold.
• Ligand Synthesis: Useful for preparing chelating ligands in coordination chemistry and catalysis.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic routes in heterocyclic chemistry.

Basic Information

Product Name	1,6-Dichloro-2,7-Naphthyridine
CAS No.	1335053-95-6
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	2,7-Naphthyridine, 1,6-dichloro-; 1,6-Dichloro-2,7-naphthyridine; 1,6-Dichloro-2,7-diazanaphthalene; 2,7-Dichloro-1,6-naphthyridine (isomer reference); Dichloronaphthyridine; DCN; CAS 1335053-95-6
EINECS	Contact for details

Quality Control

Our 1,6-Dichloro-2,7-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.