Description

3-Bromo-5-Chloropyridine-4-Carbonitrile is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active molecule research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized pyridine scaffolds.

Basic Information

Product Name	3-Bromo-5-Chloropyridine-4-Carbonitrile
CAS No.	1335052-66-8
Molecular Formula	C6H2BrClN2
Molecular Weight	217.45 g/mol
Synonyms	4-Cyano-3-bromo-5-chloropyridine; 5-Chloro-3-bromopyridine-4-carbonitrile; 3-Bromo-5-chloro-4-pyridinecarbonitrile; 3-Bromo-5-chloroisonicotinonitrile; 3-Bromo-5-chloropyridine-4-carbonitrile; 4-Pyridinecarbonitrile, 3-bromo-5-chloro-
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Chloropyridine-4-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area %)
Related Substances (HPLC)	Total impurities ≤3.0%
Any single impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.