Description

5-Bromo-3-Chloro-2-Cyclopropyl-Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, chlorine, and a cyclopropyl substituent on the pyridine ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A vital scaffold for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	5-Bromo-3-Chloro-2-Cyclopropyl-Pyridine
CAS No.	1335051-55-2
Molecular Formula	C8H7BrClN
Molecular Weight	232.50 g/mol
Synonyms	2-Cyclopropyl-5-bromo-3-chloropyridine; 3-Chloro-5-bromo-2-cyclopropylpyridine; 5-Bromo-3-chloro-2-cyclopropylpyridine; Pyridine, 5-bromo-3-chloro-2-cyclopropyl-; 1335051-55-2; 2-Cyclopropyl-3-chloro-5-bromopyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 5-Bromo-3-Chloro-2-Cyclopropyl-Pyridine is monitored through in-process controls and validated analytical methods to ensure batch-to-batch consistency and high purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.