Description

(5-Bromo-Pyridin-2-Yl)-Difluoro-Acetic Acid Methyl Ester is a high-value, multi-functional chemical building block designed for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular modifications to develop novel active ingredients. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and development of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, leveraging the pyridine and difluoroacetate motifs for enhanced biological activity.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with unique electronic properties.
• Chemical Biology Probe Development: Employed to create labeled compounds or molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(5-Bromo-Pyridin-2-Yl)-Difluoro-Acetic Acid Methyl Ester
CAS No.	1335050-83-3
Molecular Formula	C8H5BrF2NO2
Molecular Weight	266.03 g/mol
Synonyms	Methyl 2-(5-bromopyridin-2-yl)-2,2-difluoroacetate; 2,2-Difluoro-2-(5-bromo-2-pyridinyl)acetic Acid Methyl Ester; Methyl (5-Bromo-2-pyridyl)difluoroacetate; 5-Bromo-2-pyridyldifluoroacetic Acid Methyl Ester; Difluoro(5-bromo-2-pyridyl)acetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of (5-Bromo-Pyridin-2-Yl)-Difluoro-Acetic Acid Methyl Ester is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.