Description

2-Pyridinamine, 5-Bromo-3-(Difluoromethyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated pyridine core. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to enable efficient and scalable routes for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced fungicides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for designing novel ligands and functional molecules in coordination chemistry and catalysis.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex pyridine motifs into larger molecular architectures.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Pyridinamine, 5-Bromo-3-(Difluoromethyl)-
CAS No.	1335050-39-9
Molecular Formula	C7H5BrF2N2
Molecular Weight	235.03 g/mol
Synonyms	5-Bromo-3-(difluoromethyl)pyridin-2-amine; 3-(Difluoromethyl)-5-bromo-2-pyridinamine; 5-Bromo-3-(difluoromethyl)-2-aminopyridine; 2-Amino-5-bromo-3-(difluoromethyl)pyridine; 5-Bromo-3-difluoromethyl-pyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our 2-Pyridinamine, 5-Bromo-3-(Difluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The compound is moisture-sensitive; ensure containers are sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.