Description

5-Bromo-2-(2,2,2-trifluoroethyl)pyridine is a high-value halogenated and fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular modifications to develop novel compounds with enhanced properties. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and development of active ingredients, as well as in materials science for creating specialty polymers and electronic chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the bromine and trifluoroethyl groups can impart specific biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Materials Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient pyridine core and fluorine content.
• Fluorinated Compound Libraries: A valuable reagent for medicinal chemistry programs focused on building fluorinated compound libraries to explore structure-activity relationships (SAR).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular scaffold.

Basic Information

Item	Detail
Product Name	5-Bromo-2-(2,2,2-trifluoroethyl)pyridine
CAS No.	1335050-19-5
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	2-(2,2,2-Trifluoroethyl)-5-bromopyridine; 5-Bromo-2-(2,2,2-trifluoroethyl)pyridine; 5-Bromo-2-(trifluoroethyl)pyridine; 5-Bromo-2-(2,2,2-trifluoro-ethyl)pyridine; 5-Bromo-2-(trifluoroethyl)pyridine; Pyridine, 5-bromo-2-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(2,2,2-trifluoroethyl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.