Description

5-Bromo-2-(Fluoromethyl)Pyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and a fluoromethyl group, makes it a valuable intermediate for introducing specific functionalities into target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine and bromine substituents can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or photophysical properties.
• Fluorine Chemistry Building Block: The fluoromethyl group provides a handle for further fluorination or for introducing fluorine into complex molecular architectures.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	5-Bromo-2-(Fluoromethyl)Pyridine
CAS No.	1335050-09-3
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-(Fluoromethyl)-5-bromopyridine; 5-Bromo-2-fluoromethylpyridine; 5-Bromo-2-(fluoromethyl)pyridine; Pyridine, 5-bromo-2-(fluoromethyl)-; 1335050-09-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Fluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.