Description

7-Benzyl 2-tert-Butyl 2,7-Diazaspiro[3.5]Nonane-2,7-Dicarboxylate is a high-value, protected diazaspiro bicyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the development of novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing spirocyclic scaffolds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of spirocyclic drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with spirocyclic core structures.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Serves as a versatile linker or core component in the design of bifunctional molecules for targeted protein degradation.
• Material Science: Potential monomer or precursor for advanced polymers and functional materials with unique structural properties.
• Academic & Contract Research: Employed in synthetic methodology development and the exploration of new chemical space in medicinal chemistry programs.
• Scale-up & Process Chemistry: Suitable for optimization and kilogram-scale production under GMP or non-GMP conditions for clinical trial material supply.

Basic Information

Product Name	7-Benzyl 2-tert-Butyl 2,7-Diazaspiro[3.5]Nonane-2,7-Dicarboxylate
CAS No.	1334784-95-0
Molecular Formula	C20H28N2O4
Molecular Weight	360.45 g/mol
Synonyms	2,7-Diazaspiro[3.5]nonane-2,7-dicarboxylic acid, 2-(1,1-dimethylethyl) 7-(phenylmethyl) ester; tert-Butyl 7-(benzyloxycarbonyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate; 2-(tert-Butoxycarbonyl)-7-(benzyloxycarbonyl)-2,7-diazaspiro[3.5]nonane; Boc-C7-2,7-Diazaspiro[3.5]nonane-Cbz; 2,7-Diazaspiro[3.5]nonane Bis-carbamate Protected; Spirocyclic Diamine Protected Derivative; 1334784-95-0
EINECS	Contact for details

Quality Control

Our 7-Benzyl 2-tert-Butyl 2,7-Diazaspiro[3.5]Nonane-2,7-Dicarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including process research and non-GMP scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.