Description

tert-Butyl 4-(2-(Boc-Amino)Ethyl)Benzoate is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of functionalized aromatic moieties in complex molecular architectures, offering excellent stability and selectivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected amino acid derivative for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Protecting Group Strategy: The tert-butyl and Boc (tert-butoxycarbonyl) groups provide orthogonal protection for carboxylic acid and amine functionalities, enabling sequential deprotection in complex syntheses.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to modify the physicochemical properties of lead compounds.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biological target identification and validation.
• Custom Synthesis: A versatile starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke organic molecules.

Basic Information

Product Name	tert-Butyl 4-(2-(Boc-Amino)Ethyl)Benzoate
CAS No.	1334499-61-4
Molecular Formula	C18H27NO4
Molecular Weight	321.41 g/mol
Synonyms	4-[2-[(tert-Butoxycarbonyl)amino]ethyl]benzoic acid tert-butyl ester; tert-Butyl 4-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]benzoate; Boc-NH-CH2-CH2-C6H4-COO-tBu; 2-[(tert-Butoxycarbonyl)amino]ethylbenzoic acid tert-butyl ester; (4-(2-((tert-Butoxycarbonyl)amino)ethyl)phenyl) tert-butyl carbonate (incorrect but common search variant); t-Butyl 4-(2-(Boc-amino)ethyl)benzoate; BOC-4-(2-Aminoethyl)benzoic Acid t-Butyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-(Boc-Amino)Ethyl)Benzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.