Description

5-Bromo-6-Hydroxy-2-Methyl-Nicotinic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate with significant synthetic utility. This compound is valued for its role as a versatile building block in the development of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Synthesis: A versatile synthon for introducing functionalized nicotinic acid derivatives into more complex molecular architectures.
• Academic & Contract Research: Essential for medicinal chemistry programs and exploratory research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	5-Bromo-6-Hydroxy-2-Methyl-Nicotinic Acid Methyl Ester
CAS No.	1334499-25-0
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	Methyl 5-bromo-6-hydroxy-2-methylnicotinate; 5-Bromo-6-hydroxy-2-methylpyridine-3-carboxylic acid methyl ester; 2-Methyl-5-bromo-6-hydroxynicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 5-bromo-6-hydroxy-2-methyl-, methyl ester; Methyl 5-bromo-6-hydroxy-2-methyl-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Hydroxy-2-Methyl-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.