Description

4-Cyclopropylpicolinonitrile is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a picolinonitrile scaffold with a cyclopropyl substituent, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel pesticides, herbicides, and fungicides with enhanced efficacy.
• Material Science Research: Used in the development of advanced organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized nitrile chemistry.

Basic Information

Product Name	4-Cyclopropylpicolinonitrile
CAS No.	1333414-24-6
Molecular Formula	C9H8N2
Molecular Weight	144.18 g/mol
Synonyms	4-Cyclopropylpyridine-2-carbonitrile; 2-Cyano-4-cyclopropylpyridine; Picolinonitrile, 4-cyclopropyl-; 4-Cyclopropyl-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Cyclopropylpicolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.