Description

Benzyl 5-Fluorofuran-2-Carboxylate is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. Pharmaceutical research and development (R&D) departments, agrochemical innovators, and specialty chemical manufacturers are the primary industries that need this precise chemical for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorofuran moiety can enhance efficacy and environmental profile.
• Material Science Research: Acts as a monomer or precursor for developing novel fluorinated polymers and functional materials with specific electronic or surface properties.
• Chemical Biology & Proteomics: Employed as a tagging or cross-linking reagent in the study of biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Benzyl 5-Fluorofuran-2-Carboxylate
CAS No.	1333218-13-5
Molecular Formula	C12H9FO3
Molecular Weight	220.20 g/mol
Synonyms	5-Fluoro-2-furancarboxylic acid benzyl ester; Benzyl 5-fluoro-2-furoate; 5-Fluorofuran-2-carboxylic acid benzyl ester; 2-Furoic acid, 5-fluoro-, benzyl ester; Bn-5-F-2-Furoate
EINECS	Contact for details

Quality Control

Our Benzyl 5-Fluorofuran-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.