Description

Amino-Peg8-Azide is a heterobifunctional polyethylene glycol (PEG) linker featuring a primary amine and an azide group, separated by an 8-unit PEG spacer. This compound is essential for creating stable, hydrophilic, and biocompatible crosslinks in bioconjugation and materials science. It is primarily used by researchers and manufacturers in pharmaceutical development, proteomics, and advanced material synthesis to functionalize surfaces, modify biomolecules, and construct complex molecular architectures.

Application

• Bioconjugation and Click Chemistry: Utilized for site-specific labeling of proteins, antibodies, and oligonucleotides via amine-reactive chemistry and copper-free azide-alkyne cycloaddition (CuAAC).
• Drug Delivery System Development: Serves as a key building block for constructing PEGylated drug conjugates, enhancing solubility, stability, and pharmacokinetic profiles of therapeutic agents.
• Surface Functionalization: Used to modify nanoparticles, biosensors, and microarray surfaces with amine or azide groups for subsequent immobilization of biomolecules.
• Hydrogel and Biomaterial Synthesis: Acts as a crosslinking agent in the creation of hydrogels and biocompatible scaffolds for tissue engineering and 3D cell culture applications.
• Diagnostic Reagent Preparation: Employed in the synthesis of fluorescent probes, contrast agents, and other diagnostic tools requiring precise molecular attachment.
• Polymer Chemistry: Functions as a versatile monomer or modifier in the synthesis of functionalized polymers with tailored properties.

Basic Information

Item	Detail
Product Name	Amino-Peg8-Azide
CAS No.	1333154-77-0
Molecular Formula	C20H41N5O9
Molecular Weight	495.57 g/mol
Synonyms	8-Azido-3,6,9,12,15,18,21,24-octaoxapentacosan-1-amine; Azido-PEG8-amine; NH2-PEG8-N3; α-Amino-ω-azido octaethylene glycol; Amine-PEG8-azide; 8-Azido-3,6,9,12,15,18,21,24-octaoxapentacosan-1-amine hydrochloride (if applicable); PEG8 diamine azide derivative
EINECS	Contact for details

Quality Control

Our Amino-Peg8-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Amine Content (Titration)	Confirmatory

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.