Description

8-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex heterocyclic molecules, enabling the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing new therapeutic agents, particularly in the areas of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting protein kinases and other enzymatic pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• API Synthesis: Serves as a core scaffold for constructing complex imidazopyridine-based active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological processes and target validation in disease models.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and process development for clinical trial materials.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and new synthetic methodology development.

Basic Information

Product Name	8-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide
CAS No.	1332589-53-3
Molecular Formula	C10H10BrN2O2 • HBr
Molecular Weight	350.02 g/mol
Synonyms	Ethyl 8-Bromoimidazo[1,2-a]pyridine-2-carboxylate Hydrobromide; 8-Bromoimidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester HBr Salt; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-, ethyl ester, hydrobromide; 1332589-53-3; Ethyl 8-bromo-imidazo[1,2-a]pyridine-2-carboxylate hydrobromide salt; 8-Bromo-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester HBr; 8-Bromoimidazo[1,2-a]pyridine-2-carboxylate ethyl ester hydrobromide
EINECS	Contact for details

Quality Control

Our 8-Bromo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester Hydrobromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.