Description

Methyl 4-Bromo-3-(Difluoromethoxy)Benzoate is a high-purity, advanced pharmaceutical intermediate with a distinct difluoromethoxy-bromo benzoate structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for constructing novel molecules with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the difluoromethoxy group can enhance biological activity and stability.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromo and difluoromethoxy-substituted benzoate moiety into more complex molecular architectures.

Basic Information

Product Name	Methyl 4-Bromo-3-(Difluoromethoxy)Benzoate
CAS No.	1331943-86-2
Molecular Formula	C9H7BrF2O3
Molecular Weight	281.05 g/mol
Synonyms	Benzoic acid, 4-bromo-3-(difluoromethoxy)-, methyl ester; Methyl 4-bromo-3-(difluoromethoxy)benzoate; 4-Bromo-3-(difluoromethoxy)benzoic acid methyl ester; 3-(Difluoromethoxy)-4-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-3-(Difluoromethoxy)Benzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.