Description

N,N'-Bis(Benzyloxycarbonyl)-L-Lysine 4-Nitrobenzyl Ester is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a crucial building block for the controlled construction of peptides and other complex molecules, offering selective deprotection pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical tools. The product is supplied to the global market with a focus on consistent quality and reliable supply chain integrity.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled incorporation of lysine residues with orthogonal protecting groups.
• Solution-Phase Peptide Chemistry: Enabling the synthesis of specific peptide sequences in solution, particularly where selective deprotection is required.
• Pharmaceutical Research & Development: A vital precursor in the R&D of peptide-based drugs, prodrugs, and targeted bioactive compounds.
• Bioconjugation and Labeling: Facilitating the site-specific attachment of probes, tags, or other molecules to peptides or proteins via the ε-amino group of lysine.
• Academic Research: Used in university and institutional labs for studying peptide structure-activity relationships and developing new synthetic methodologies.
• Custom Synthesis Services: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized peptides for clients.

Basic Information

Item	Details
Product Name	N,N'-Bis(Benzyloxycarbonyl)-L-Lysine 4-Nitrobenzyl Ester
CAS No.	1331899-68-3
Molecular Formula	C28H29N3O8
Molecular Weight	535.55 g/mol
Synonyms	Nα,Nε-Bis(Z)-L-Lysine 4-Nitrobenzyl Ester; Z-Lys(Z)-ONb; H-Lys(Z2)-ONb; Nα-Carbobenzoxy-Nε-carbobenzoxy-L-lysine 4-nitrobenzyl ester; (S)-2-((((Benzyloxy)carbonyl)amino)-6-((((benzyloxy)carbonyl)amino)hexanoic acid 4-nitrobenzyl ester; Lysine derivative, N2,N6-bis(benzyloxycarbonyl)-, 4-nitrobenzyl ester; Boc-Lys(Z)-ONb (common misnomer, note correct protecting groups)
EINECS	Contact for details

Quality Control

Every batch of N,N'-Bis(Benzyloxycarbonyl)-L-Lysine 4-Nitrobenzyl Ester is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and conformity to specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep the container sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.