Description

tert-Butyl 7-Bromo-5-Oxa-2-Azaspiro[3.4]Octane-2-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic applications. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel bioactive compounds.
• Spirocyclic Compound Synthesis: Serves as a versatile precursor for constructing complex spiroheterocyclic frameworks, which are privileged structures in drug discovery.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	tert-Butyl 7-Bromo-5-Oxa-2-Azaspiro[3.4]Octane-2-Carboxylate
CAS No.	1330765-30-4
Molecular Formula	C11H18BrNO3
Molecular Weight	292.17 g/mol
Synonyms	7-Bromo-2-[(tert-butoxy)carbonyl]-5-oxa-2-azaspiro[3.4]octane; 2-Boc-7-bromo-5-oxa-2-azaspiro[3.4]octane; tert-Butyl 7-bromo-5-oxa-2-azaspiro[3.4]octane-2-carboxylate; 1330765-30-4; 7-Bromo-5-oxa-2-azaspiro[3.4]octane-2-carboxylic acid tert-butyl ester; Boc-7-bromo-5-oxa-2-azaspiro[3.4]octane; (7-Bromo-5-oxa-2-azaspiro[3.4]oct-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Bromo-5-Oxa-2-Azaspiro[3.4]Octane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.