Description

tert-Butyl 5-Amino-2-Azaspiro[3.3]Heptane-2-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with potential therapeutic applications. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing next-generation drugs, particularly in areas like central nervous system (CNS) disorders and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting G protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its rigid, three-dimensional spirocyclic structure.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• CNS Drug Discovery: Employed in creating compounds for potential treatments of neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	tert-Butyl 5-Amino-2-Azaspiro[3.3]Heptane-2-Carboxylate
CAS No.	1330765-13-3
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	2-Azaspiro[3.3]heptane-2-carboxylic acid, 5-amino-, 1,1-dimethylethyl ester; 5-Amino-2-azaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester; tert-Butyl 5-amino-2-azaspiro[3.3]heptane-2-carboxylate; 2-tert-Butoxycarbonyl-5-amino-2-azaspiro[3.3]heptane; 5-Amino-2-Boc-2-azaspiro[3.3]heptane; Boc-5-Amino-2-azaspiro[3.3]heptane; 2-Azaspiro[3.3]heptan-5-amine, 2-(tert-butoxycarbonyl)-
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Amino-2-Azaspiro[3.3]Heptane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.