Description

tert-Butyl 3-(Hydroxymethyl)-1-Methyl-6,7-Dihydro-1H-Pyrazolo[4,3-C]Pyridine-5(4H)-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex fused heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel small-molecule drug candidates.
• Oncology Research: Used in the research and synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Central Nervous System (CNS) Drug Discovery: Employed in creating compounds for neurological and psychiatric disorder research.
• Medicinal Chemistry & Process R&D: Provides a versatile scaffold for structure-activity relationship (SAR) studies and route scouting.
• Contract Manufacturing (CMO/CDMO): Supplied to contract organizations for cGMP-scale production of clinical trial materials.
• Academic & Industrial Research: Utilized in chemical biology and probe discovery for studying biological pathways.

Basic Information

Product Name	tert-Butyl 3-(Hydroxymethyl)-1-Methyl-6,7-Dihydro-1H-Pyrazolo[4,3-C]Pyridine-5(4H)-Carboxylate
CAS No.	1330765-07-5
Molecular Formula	C14H23N3O3
Molecular Weight	281.35 g/mol
Synonyms	1-Methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylic acid, 3-(hydroxymethyl)-, 1,1-dimethylethyl ester; tert-Butyl 3-(hydroxymethyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-5-carboxylate; 5-tert-Butoxycarbonyl-1-methyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-c]pyridine-3-methanol; BOC-Protected Pyrazolopyridine Intermediate; 1330765-07-5
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Hydroxymethyl)-1-Methyl-6,7-Dihydro-1H-Pyrazolo[4,3-C]Pyridine-5(4H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.