Description

2-(n-Boc-Aminomethyl)-4-Methylpyridine is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds for constructing complex molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or spacer component in the design of peptide analogs and proteolysis-targeting chimeras (PROTACs).
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its pyridine-based structure.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Integral for creating molecular probes and tools to study biological pathways and protein function.
• Custom Synthesis & Scale-up: Supports contract research and manufacturing organizations (CROs/CMOs) in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2-(n-Boc-Aminomethyl)-4-Methylpyridine
CAS No.	1330755-53-7
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	2-((tert-Butoxycarbonylamino)methyl)-4-methylpyridine; 2-[(Boc-amino)methyl]-4-picoline; 4-Methyl-2-((tert-butoxycarbonylamino)methyl)pyridine; 2-(Boc-aminomethyl)-4-methylpyridine; tert-Butyl N-[(4-methylpyridin-2-yl)methyl]carbamate; Boc-4-methyl-2-picolylamine; 2-(N-Boc-aminomethyl)-4-methylpyridine; 2-(tert-Butoxycarbonylaminomethyl)-4-methylpyridine
EINECS	Contact for details

Quality Control

Our 2-(n-Boc-Aminomethyl)-4-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.