Description

Ethyl 6-(2,5-Difluorophenyl)Pyridine-2-Carboxylate is a high-purity, fluorinated pyridine derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which enables the construction of complex pharmacophores and functional materials. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by specialty chemical manufacturers focused on creating novel active ingredients and electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl and pyridine motifs contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) producing specialized compounds for client pipelines.

Basic Information

Product Name	Ethyl 6-(2,5-Difluorophenyl)Pyridine-2-Carboxylate
CAS No.	1330750-30-5
Molecular Formula	C14H11F2NO2
Molecular Weight	263.24 g/mol
Synonyms	Ethyl 6-(2,5-difluorophenyl)picolinate; 2-Pyridinecarboxylic acid, 6-(2,5-difluorophenyl)-, ethyl ester; 6-(2,5-Difluorophenyl)-2-pyridinecarboxylic acid ethyl ester; Ethyl 6-(2,5-difluorophenyl)-2-pyridinecarboxylate; 1330750-30-5; 6-(2,5-Difluorophenyl)picolinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-(2,5-Difluorophenyl)Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.