Description

1-(2,3-Dichlorophenyl)-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a reactive isocyanide group and a dichlorophenyl-tosylmethyl scaffold. This compound matters as a critical intermediate in advanced organic synthesis, enabling the construction of complex heterocyclic and pharmaceutical frameworks through multicomponent reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in multicomponent reactions like the Ugi and Passerini reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by providing a versatile chemical handle for structural diversification.
• Chemical Biology & Probe Development: Employed in the creation of activity-based probes and bioconjugation reagents due to the reactive isocyanide functionality.
• Material Science: Acts as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic pathways in university and CRO laboratories.

Basic Information

Product Name	1-(2,3-Dichlorophenyl)-1-Tosylmethyl Isocyanide
CAS No.	1330529-80-0
Molecular Formula	C15H11Cl2NO2S
Molecular Weight	352.22 g/mol
Synonyms	1-(2,3-Dichlorophenyl)-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-Isocyano-1-(2,3-dichlorophenyl)-1-tosylmethane; 1-(2,3-Dichlorophenyl)-1-(p-tolylsulfonyl)methyl isocyanide; 1-(2,3-Dichlorophenyl)-1-(tosylmethyl)isocyanide; 1-(2,3-Dichlorophenyl)-1-(4-methylbenzenesulfonyl)methyl isocyanide; 1-(2,3-Dichlorophenyl)-1-(p-toluenesulfonyl)methyl isocyanide; 1-(2,3-Dichlorophenyl)-1-(4-methylphenylsulfonyl)methyl isocyanide
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dichlorophenyl)-1-Tosylmethyl Isocyanide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.