Description

1-(2,6-Dichlorophenyl)-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a reactive isocyanide functional group. This compound is valued for its role as a key intermediate in advanced synthetic methodologies, particularly in the construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for constructing complex nitrogen-containing heterocycles via multicomponent reactions (MCRs) like the Ugi reaction.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its structural motifs to create molecules with specific biological activity.
• Chemical Biology & Probe Development: Serves as a versatile reagent for creating chemical probes and bioconjugates to study biological processes and protein functions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored properties.
• Academic & Contract Research: Essential for methodological development in organic synthesis and for exploring new reaction pathways in university and CRO laboratories.

Basic Information

Product Name	1-(2,6-Dichlorophenyl)-1-Tosylmethyl Isocyanide
CAS No.	1330529-78-6
Molecular Formula	C15H11Cl2NO2S
Molecular Weight	340.22 g/mol
Synonyms	1-Isocyano-1-(2,6-dichlorophenyl)-2-tosylethane; 1-(2,6-Dichlorophenyl)-2-(p-tolylsulfonyl)-1-isocyanoethane; 2,6-Dichloro-α-isocyano-p-tolylsulfonyltoluene; Tosylmethyl Isocyanide (TosMIC) derivative; 2,6-Dichlorobenzyl Isocyanide Tosylate Derivative; (2,6-Dichlorophenyl)(tosylmethyl)isocyanide; 1-(2,6-Dichlorophenyl)-1-[(4-methylphenyl)sulfonyl]methyl Isocyanide
EINECS	Contact for details

Quality Control

Our 1-(2,6-Dichlorophenyl)-1-Tosylmethyl Isocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.