Description

1-p-Tolyl-1-Tosylmethyl Isocyanide is a specialized organic building block featuring both an isocyanide and a tosylmethyl functional group. This compound matters for its unique reactivity profile, enabling its use as a versatile precursor in the synthesis of complex heterocycles and functionalized molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-component synthesis of nitrogen-containing heterocycles with potential biological activity.
• Agrochemical Research: Used in the development of new active ingredients by providing a reactive handle for structural diversification.
• Material Science: Serves as a monomer or functionalizing agent in the design of specialty polymers and advanced materials.
• Academic & Discovery Chemistry: A valuable reagent in methodology development and library synthesis for high-throughput screening.
• Peptidomimetics: Employed in the construction of peptide analogs and isocyanide-based multicomponent reactions (IMCRs).

Basic Information

Product Name	1-p-Tolyl-1-Tosylmethyl Isocyanide
CAS No.	1330529-37-7
Molecular Formula	C16H15NO2S
Molecular Weight	285.36 g/mol
Synonyms	1-Tosyl-1-(p-tolyl)methyl isocyanide; 1-(4-Methylphenyl)-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-(p-Tolyl)-1-(tosyl)methyl isocyanide; 1-(4-Methylphenyl)-1-[(4-methylbenzenesulfonyl)]methyl isocyanide; Isocyanide, [[(4-methylphenyl)sulfonyl](4-methylphenyl)methyl]-; [Tosyl(p-tolyl)methyl] isocyanide
EINECS	Contact for details

Quality Control

Our 1-p-Tolyl-1-Tosylmethyl Isocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.