Description

1-(2,3-Dimethoxyphenyl)-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a unique isocyanide functional group. This compound is of significant value in advanced organic synthesis, particularly for its role in facilitating complex multi-component reactions. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel heterocyclic scaffolds and active pharmaceutical ingredient (API) intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides.
• Multi-Component Reaction (MCR) Chemistry: Serves as a critical reactant in Passerini and Ugi-type reactions to efficiently build molecular complexity.
• Heterocyclic Compound Synthesis: Employed for the construction of diverse nitrogen-containing heterocycles, which are prevalent in medicinal chemistry.
• Chemical Biology Probes: Utilized in the development of isocyanide-based probes for studying biological systems and protein labeling.
• Material Science Research: Investigated as a monomer or building block for novel polymers and functional materials.

Basic Information

Product Name	1-(2,3-Dimethoxyphenyl)-1-Tosylmethyl Isocyanide
CAS No.	1330186-53-2
Molecular Formula	C17H17NO4S
Molecular Weight	331.39 g/mol
Synonyms	1-(2,3-Dimethoxyphenyl)-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-Isocyano-1-(2,3-dimethoxyphenyl)-1-tosylmethane; 1-Tosyl-1-(2,3-dimethoxyphenyl)methyl isocyanide; 1-(2,3-Dimethoxyphenyl)-1-(p-tolylsulfonyl)methyl isocyanide; 1-(p-Toluenesulfonyl)-1-(2,3-dimethoxyphenyl)methyl isocyanide; TosMIC derivative (2,3-dimethoxy); (2,3-Dimethoxyphenyl)(isocyanomethyl)sulfonylbenzene
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dimethoxyphenyl)-1-Tosylmethyl Isocyanide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.